Global demand for natural killer cells therapeutics market was valued at approximately USD 1.41 billion in 2018 and is expected to generate revenue of around USD 4.19 billion by end of 2025, growing at a CAGR of around 16.9% between 2019 and 2025. Natural killer cells, which are effector lymphocytes of the innate immune system, regulate various tumor types and microbial infections by preventing their spread and ensuing tissue damage. Similar to CAR-T cell treatment, natural killer cell therapy is a type of immunotherapy. Similar to T-cells, NK cells are immune system components that fight pathogens and other cancerous cells. However, NK cells are not specialized to particular antigens like T-cells are.
Large granular lymphocytes known as natural killer (NK) cells are rapid to react to a pathogenic threat. They are also in charge of making cytokines that regulate the immune system. Additionally, they play a crucial role in the human innate immune system. The primary function of NK cells is to trigger an immune response against viral infections and cancers.
The factor driving the global market for natural killer cell treatments is the rise in the use of NK cells to treat infections, cancer, and liver ailments. Additionally, NK cells are essential for tumor immune surveillance, which promotes the widespread use of NK treatments. The increase in research and development for the creation of bi-specific antibodies for activating NK cells to eradicate tumor cells, as well as the growing public awareness of various immunotherapies, drive the expansion of the global market. However, the development of natural killer cell therapies is constrained by the lack of selectivity and low in vivo survival of the cells.
The market for therapeutic usage of natural killer cells, by users
According to end-users, the natural killer cells therapeutics market is segmented into research centres & institutions, hospitals, and others. NK cells and immunological memory enhancements, cell-based therapeutics, and stress-induced self-recognition are only a few of the ongoing R&D projects. Additionally, a few immuno-monitoring investigations are being conducted to ascertain the utilisation of NK cells. NK cell therapies are applied in medical facilities to cure tumours through genetic modification. Due to their capacity to recognise altered cells, these cells are also employed as a therapeutic tool to treat immunoproliferative disorders, different malignancies, gastrointestinal problems, and infectious diseases.
- NKT Therapeutics Inc.
- Nkarta Therapeutics, Inc.
- Nantkwest Inc.
- Innate Pharma S.A.
- Glycostem Therapeutics BV
- Fortress Biotech
- Fate Therapeutics
- Celgene Corporation,
- Affimed N.V.
- Ziopharm Oncology Inc.
Natural Killer Cells Therapeutics Market Trends:
One of the main drivers of the market growth is the sharp increase in the number of people suffering from cancer, infectious diseases, and liver problems. This can be related to unhealthy eating habits, a lack of physical activity, rising air pollution, and an increase in people using tobacco and alcohol. The growing geriatric population around the world is another growth-inducing factor driving the market for NK cells treatments, as the chance of acquiring cancer grows sharply with age.
Additionally, because cancer patients’ immune responses are insufficient, health businesses are creating novel techniques and technology to enhance the immune response through allogeneic, over-the-counter NK cell-based medicines. Additionally, additional clinical trials are concentrating on tumour-targeted antibody approaches to maximise the therapeutic efficacy of NK-cell-based therapy while lowering risks and toxicities. A positive picture for the sector is also being created by the sponsorship of financial programmes for cancer patients by several governments.
Key Market Segmentation:
The report segment of global natural killer cells therapeutics market as follows: Therapeutics
- NK Cell Directed Antibodies
- NK Cell Therapies
- Immunoproliferative Disorders
- Gastrointestinal Diseases
- Other Applications
- Research Centers & Institutes
- Other End Users
- North America
- Asia Pacific
- Latin America
- Middle East and Africa
Cancer Sector to Provide Enticing Opportunities
The natural killer (NK) cell treatments market may be segmented based on application into cancer, immune-proliferative disorders, gastrointestinal diseases, and others.
In 2027, it is anticipated that the natural killer (NK) cell therapies market would be dominated by the cancer segment.
The domination of this market can be linked to the rise in cancer prevalence rates worldwide.
Extensive research of the healthcare sector with an emphasis on the examination of worldwide market trends is called “Natural Killer Cells Therapeutics Market Analysis to 2028.” With a thorough market segmentation by therapies, applications, end-users, and geography, the study seeks to give an overview of the natural killer cells therapeutics market. The market for therapeutic natural killer cells is anticipated to expand rapidly during the coming years. The research covers major trends and opportunities in the market and delivers critical information on the market status of the top competitors in the natural killer cell therapeutics market.
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Impacts of the COVID-19 Pandemic –
Most industries across the world have been negative impacts over the last 18 months. This can be attributed to significant disruptions experienced by their respective manufacturing and supply-chain operations as a result of various precautionary lockdowns, as well as other restrictions that were enforced by governing authorities across the globe.
The same applies to the global Natural Killer Cells Therapeutics Market.
Moreover, consumer demand has also subsequently reduced as individuals are now more keen on eliminating non-essential expenses from their respective budgets as the general economic status of most individuals has been severely affected by this outbreak.
These aforementioned elements are expected to burden the revenue trajectory of the global Natural Killer Cells Therapeutics Market over the forecast timeline.
However, as respective governing authorities begin to lift these enforced lockdowns, the global Natural Killer Cells Therapeutics Market is expects to recover accordingly.